ea0015p324 | Steroids | SFEBES2008
Mowatt Christopher J
, Vassiliadi Dimitra A
, Holder Geoff
, Clark Penny
, Bion Julian
, Stewart Paul M
, Arlt Wiebke
Stress results in activation of the hypothalamicpituitaryadrenal axis with increased circulating cortisol. It has been argued that a syndrome of relative adrenal insufficiency is common in critically ill patients. Patients who fail to increase their cortisol by >250 nmol/30 min following the administration of 250 μg ACTH in the short synacthen test (SST) have been reported to have a higher mortality (JAMA 2000, 283 10381045)...